| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed |
|---|---|---|---|---|---|---|---|
| 1 | Collinsville | A | Bircher | Conrad | Driscoll | Rogers | 1:45.00 |
| 2 | Highland | A | Leftwich | Miller | Austin | Rittenhouse | 1:45.00 |
| 3 | Pleasant Plains | A | Veesenmeyer | Morley | Kmett | Shea | 1:44.00 |
| 4 | Jersey | A | Arbuthnot | Guardado | Fester | Bartels | 1:43.00 |
| 5 | Granite City | A | Smith | Webster | Ford | Burris | 1:38.50 |
| 6 | Triad | A | Pottorff | Jones | James | Jones | 1:42.00 |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed |
|---|---|---|---|---|---|---|---|
| 1 | Roxana | A | Wilburn | Pluester | Flener | Troxtell | 1:38.50 |
| 2 | Columbia | A | Hall | Bieber | Mathews | Little | 1:38.00 |
| 3 | Alton Marquette | A | Bethal | Obanigba | guerin | Williams | 1:37.60 |
| 4 | Belleville West | A | Jenkins | Young | Williams | Perkins | 1:36.00 |
| 5 | Alton | A | Davis | Bratton | Boey | Stewart | 1:33.78 |
| 6 | Mascoutah | A | Wills | Johnson | Toolie | McDonald | 1:35.00 |