| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed |
|---|---|---|---|---|---|---|---|
| 4 | Vashon | A | Taylor | Mosley | Boyd | Butler | 58.91 |
| 5 | Kirkwood | A | Beaumont | Bert | Pride | Wright | 55.30 |
| 6 | Lanphier | A | Patterson | Jackson | Davis | Lewis | 55.50 |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed |
|---|---|---|---|---|---|---|---|
| 2 | Riverview Gardens | A | Robinson | Green | Smith | Davis | 55.00 |
| 3 | Proviso East | A | Gay | Kimble | Lawson | Robinson-Thomas | 54.10 |
| 4 | Morgan Park | A | Jackson | King | McGowan | Sterling | 53.00 |
| 5 | Ritenour | A | Royal | Jones | French | McGhee | 53.00 |
| 6 | Marian Catholic (C.H.) | A | Peoples | Crozier | Ward | Price | 53.00 |
| 7 | St. Laurence | A | Bartling | Chinn | Holubecki | Kelly | 53.81 |
| 8 | Hazelwood East | A | Carter | Glanton | Fitch | Easley | 54.32 |
| 9 | SIUE Charter | A | Black | Spiller | Leech | Parker | 55.10 |
| Lane | Team | Squad | Athlete 1 | Athlete 2 | Athlete 3 | Athlete 4 | Seed |
|---|---|---|---|---|---|---|---|
| 1 | Southeast (Springfield) | A | Lowery | Shelby | Howze | Hobson | 53.00 |
| 2 | McCluer North | A | Buckley | Murphy | Goforth | Love | 52.31 |
| 3 | Belleville East | A | Chism | Armour | Durrah | Bacon | 49.69 |
| 4 | East St. Louis | A | Jones | Lampley | Graham | Glenn | 49.00 |
| 5 | Kenwood | A | Carr | Shepherd | Thomas | Parker | 48.00 |
| 6 | Cardinal Ritter | A | brady | Tiller | Watkins | James | 48.00 |
| 7 | Hazelwood Central | A | Madison | Reed | McKenzie | Wilkins | 49.66 |
| 8 | Proviso West | A | Mason | Brown | White | Butler | 51.00 |
| 9 | Hazelwood West | A | Cuthlow-Davis | Jones | Young | Squires | 52.76 |